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1

Gene profile analysis implicates Klotho as an important contributor to aging changes in brain white matter of the rhesus monkey

James A. Duce, Sonia Podvin, William Hollander, David Kipling, Douglas L. Rosene, Carmela R. Abraham

Journal:

Year:

2008

Language:

english

File:

PDF, 760 KB

english, 2008

2

Candidate molecular pathways of white matter vulnerability in the brain of normal aging rhesus monkeys

Robinson, Amy A., Abraham, Carmela R., Rosene, Douglas L.

Journal:

Year:

2018

Language:

english

File:

PDF, 2.51 MB

english, 2018

3

Amyloid Precursor Protein Is Synthesized by Retinal Ganglion Cells, Rapidly Transported to the Optic Nerve Plasma Membrane and Nerve Terminals, and Metabolized

Peter J. Morin, Carmela R. Abraham, Anil Amaratunga, Robin J. Johnson, Glenn Huber, Julie H. Sandell, Richard E. Fine

Journal:

Journal of Neurochemistry

Year:

1993

Language:

english

File:

PDF, 3.19 MB

english, 1993

4

Small-molecule Klotho enhancers as novel treatment of neurodegeneration

Abraham, Carmela R, Chen, CiDi, Cuny, Gregory D, Glicksman, Marcie A, Zeldich, Ella

Journal:

Future Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 653 KB

english, 2012

5

O1-03-07: Klotho, aging and Alzheimer's

Carmela R. Abraham, Sonia Podvin, Gwendalyn King, Ann McKee, Isabel Carreras, Alpaslan Dedeoglu, Ci-Di Chen

Journal:

Alzheimer's & Dementia

Year:

2008

Language:

english

File:

PDF, 70 KB

english, 2008

6

Hypothesis: β amyloid precursor protein is a key sorting and targeting receptor for neuropeptidases

Fine, Richard E., Abraham, Carmela R.

Journal:

Year:

1997

Language:

english

File:

PDF, 707 KB

english, 1997

7

Identification of novel small molecules that elevate Klotho expression

King, Gwendalyn D., Chen, CiDi, Huang, Mickey M., Zeldich, Ella, Brazee, Patricia L., Schuman, Eli R., Robin, Maxime, Cuny, Gregory D., Glicksman, Marcie A., Abraham, Carmela R.

Journal:

Biochemical Journal

Year:

2012

Language:

english

File:

PDF, 582 KB

english, 2012

8

Association between bleomycin hydrolase and Alzheimer's disease in caucasians

Dr. Lindsay A. Farrer, Carmela R. Abraham, Jonathan L. Haines, Ekaterina A. Rogaeva, Youqiang Song, Walker T. McGraw, Nicholas Brindle, Smita Premkumar, William K. Scott, Larry H. Yamaoka, Ann M. Saun

Journal:

Annals of Neurology

Year:

1998

Language:

english

File:

PDF, 416 KB

english, 1998

9

Age-related molecular reorganization at the node of Ranvier

Jason D. Hinman, Alan Peters, Howard Cabral, Douglas L. Rosene, William Hollander, Matthew N. Rasband, Carmela R. Abraham

Journal:

The Journal of Comparative Neurology

Year:

2006

Language:

english

File:

PDF, 852 KB

english, 2006

10

Age-dependent accumulation of ubiquitinated 2′,3′-cyclic nucleotide 3′-phosphodiesterase in myelin lipid rafts

Jason D. Hinman, Ci-Di Chen, Sun-Young Oh, William Hollander, Carmela R. Abraham

Journal:

Year:

2008

Language:

english

File:

PDF, 541 KB

english, 2008

11

Amyloid precursor protein interacts with notch receptors

Sun Young Oh, Aviva Ellenstein, Ci-Di Chen, Jason D. Hinman, Eric A. Berg, Catherine E. Costello, Rina Yamin, Rachael L. Neve, Carmela R. Abraham

Journal:

Journal of Neuroscience Research

Year:

2005

Language:

english

File:

PDF, 742 KB

english, 2005

12

Monoclonal Antibodies Against the Human Metalloprotease EC 3.4.24.15 Label Neurofibrillary Tangles in Alzheimer's Disease Brain

Kelly J. Conn, Michael Pietropaolo, Shyr-Te Ju, Carmela R. Abraham

Journal:

Journal of Neurochemistry

Year:

1996

Language:

english

File:

PDF, 964 KB

english, 1996

13

Activation of calpain-1 in myelin and microglia in the white matter of the aged rhesus monkey

Jason D. Hinman, James A. Duce, Robert A. Siman, William Hollander, Carmela R. Abraham

Journal:

Journal of Neurochemistry

Year:

2004

Language:

english

File:

PDF, 444 KB

english, 2004

14

Oxysterol-binding protein-1 (OSBP1) modulates processing and trafficking of the amyloid precursor protein

Celina V Zerbinatti, Joanna M Cordy, Ci-Di Chen, Maria Guillily, Sokreine Suon, William J Ray, Guy R Seabrook, Carmela R Abraham, Benjamin Wolozin

Journal:

Molecular Neurodegeneration

Year:

2008

Language:

english

File:

PDF, 1.33 MB

english, 2008

15

Acyl peptide hydrolase degrades monomeric and oligomeric amyloid-beta peptide

Rina Yamin, Cheng Zhao, Peter B O'Connor, Ann C McKee, Carmela R Abraham

Journal:

Molecular Neurodegeneration

Year:

2009

Language:

english

File:

PDF, 786 KB

english, 2009

16

What’s Behind the Decline? The Role of White Matter in Brain Aging

Jason D. Hinman, Carmela R. Abraham

Journal:

Neurochemical Research

Year:

2007

Language:

english

File:

PDF, 316 KB

english, 2007

17

Unusual brominations with N-bromopolymaleimide

Carmela Yaroslavsky, Abraham Patchornik, Ephraim Katchalski

Journal:

Tetrahedron Letters

Year:

1970

Language:

english

File:

PDF, 217 KB

english, 1970

18

Isolation of Low-Molecular-Weight Proteins from Amyloid Plaque Fibers in Alzheimer's Disease

Dennis J. Selkoe, Carmela R. Abraham, Marcia B. Podlisny, Lawrence K. Duffy

Journal:

Journal of Neurochemistry

Year:

1986

Language:

english

File:

PDF, 3.34 MB

english, 1986

19

α1-Antichymotrypsin Binding to Alzheimer Aβ Peptides Is Sequence Specific and Induces Fibril Disaggregation In Vitro

Paul E. Fraser, Jack T. Nguyen, Donald R. McLachlan, Carmela R. Abraham, Daniel A. Kirschner

Journal:

Journal of Neurochemistry

Year:

1993

Language:

english

File:

PDF, 1.87 MB

english, 1993

20

Visualization of APP dimerization and APP-Notch2 heterodimerization in living cells using bimolecular fluorescence complementation

Ci-Di Chen, Sun-Young Oh, Jason D. Hinman, Carmela R. Abraham

Journal:

Journal of Neurochemistry

Year:

2006

Language:

english

File:

PDF, 668 KB

english, 2006

21

Acyl peptide hydrolase, a serine proteinase isolated from conditioned medium of neuroblastoma cells, degrades the amyloid-β peptide

Rina Yamin, Sandipan Bagchi, Rick Hildebrant, Andrea Scaloni, Russell L. Widom, Carmela R. Abraham

Journal:

Journal of Neurochemistry

Year:

2007

Language:

english

File:

PDF, 738 KB

english, 2007

22

Cell-type dependent modulation of Notch signaling by the amyloid precursor protein

Sun Young Oh, Ci-Di Chen, Carmela R. Abraham

Journal:

Journal of Neurochemistry

Year:

2010

Language:

english

File:

PDF, 404 KB

english, 2010

23

α1-Antichymotrypsin Inhibits Aβ Degradation in Vitro and in Vivo

CARMELA R. ABRAHAM, WALKER T. McGRAW, FRANCHOT SLOT, RINA YAMIN

Journal:

Annals of the New York Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 190 KB

english, 2000

24

Antibodies to paired helical filaments in Alzheimer's disease do not recognize normal brain proteins

Ihara, Yasuo, Abraham, Carmela, Selkoe, Dennis J.

Journal:

Year:

1983

File:

PDF, 844 KB

1983

25

Central nervous system damage produced by expression of the HIV-1 coat protein gpl20 in transgenic mice

Toggas, Stephanie M., Masliah, Eliezer, Rockenstein, Edward M., Rail, Glenn F., Abraham, Carmela R., Mucke, Lennart

Journal:

Year:

1994

File:

PDF, 929 KB

1994

26

Demonstration of plasma proteinase inhibitors in β2-microglobulin amyloid deposits

Campistol, Josep M, Shirahama, Tsuranobu, Abraham, Carmela R, Rodgers, Orville G, Solé, Manel, Cohen, Alan S, Skinner, Martha

Journal:

Kidney International

Year:

1992

Language:

english

File:

PDF, 1014 KB

english, 1992

27

Alzheimer's Disease: Recent Advances in Understanding the Brain Amyloid Deposits

Abraham, Carmela R., Potter, Huntington

Journal:

Year:

1989

File:

PDF, 1.12 MB

1989

28

Astrocytic hypertrophy and altered GFAP degradation with age in subcortical white matter of the rhesus monkey

Jacob A Sloane, William Hollander, Douglas L Rosene, Mark B Moss, Thomas Kemper, Carmela R Abraham

Journal:

Year:

2000

Language:

english

File:

PDF, 1.04 MB

english, 2000

29

Platelets and DAMI megakaryocytes possess β-secretase-like activity

Carmela R Abraham, Derek C.L Marshall, Heather E Tibbles, Kimberly Otto, Heidi J Long, Andrea M Billingslea, Ryan Hastey, Robin Johnson, Richard E Fine, Sally J Smith, Elizabeth R Simons, Theresa A Da

Journal:

Journal of Laboratory and Clinical Medicine

Year:

1999

Language:

english

File:

PDF, 2.50 MB

english, 1999

30

Glandular Trichomes of Fagonia L. (Zygophyllaceae) Species: Structure, Development and Secreted Materials

ABRAHAM FAHN, CARMELA SHIMONY

Journal:

Annals of Botany

Year:

1996

Language:

english

File:

PDF, 581 KB

english, 1996

31

Ultrastructure and Secretion of the Secretory Cells of Two Species ofFagoniaL. (Zygophyllaceae)

ABRAHAM FAHN, CARMELA SHIMONY

Journal:

Annals of Botany

Year:

1998

Language:

english

File:

PDF, 3.70 MB

english, 1998

32

Nectary Structure and Ultrastructure of Unisexual Flowers of Ecballium elaterium(L.) A. Rich. (Cucurbitaceae) and their Presumptive Pollinators

Abraham Fahn, Carmela Shimony

Journal:

Annals of Botany

Year:

2001

Language:

english

File:

PDF, 1.18 MB

english, 2001

33

Allele ϵ4 of Apolipoprotein E Shows a Dose Effect on Age at Onset of Pick Disease

Lindsay A. Farrer, Carmela R. Abraham, Ladislav Volicer, Elizabeth J. Foley, Neil W. Kowall, Ann C. McKee, John M. Wells

Journal:

Experimental Neurology

Year:

1995

File:

PDF, 948 KB

1995

34

A calcium-activated protease from Alzheimer's disease brain cleaves at the N-terminus of the amyloid β-protein

Carmela R. Abraham, James Driscoll, Huntington Potter, William E. Van Nostrand, Paul Tempst

Journal:

Biochemical and Biophysical Research Communications

Year:

1991

Language:

english

File:

PDF, 660 KB

english, 1991

35

A calcium-stimulated serine protease from monkey brain degrades the β-amyloid precursor protein

Bronwyn L. Razzaboni, Gregory Papastoitsis, Edward H. Koo, Carmela R. Abraham

Journal:

Year:

1992

Language:

english

File:

PDF, 1.97 MB

english, 1992

36

Protection against hemorrhagic shock in the cat by human plasma containing endotoxin-specific antibodies

Stephen L. Gaffin, Zina Grinberg, Carmela Abraham, J. Birkhan, Yael Shechter

Journal:

Journal of Surgical Research

Year:

1981

Language:

english

File:

PDF, 314 KB

english, 1981

37

Activation of early components of complement targets myelin and oligodendrocytes in the aged rhesus monkey brain

James A. Duce, William Hollander, Rebecca Jaffe, Carmela R. Abraham

Journal:

Neurobiology of Aging

Year:

2006

Language:

english

File:

PDF, 720 KB

english, 2006

38

Serum paraoxonase activity is associated with variants in the PON gene cluster and risk of Alzheimer disease

Porat M. Erlich, Kathryn L. Lunetta, L. Adrienne Cupples, Carmela R. Abraham, Robert C. Green, Clinton T. Baldwin, Lindsay A. Farrer

Journal:

Neurobiology of Aging

Year:

2012

Language:

english

File:

PDF, 3.68 MB

english, 2012

39

Astroglial Expression of Human α1-Antichymotrypsin Enhances Alzheimer-like Pathology in Amyloid Protein Precursor Transgenic Mice

Lennart Mucke, Gui-Qiu Yu, Lisa McConlogue, Edward M. Rockenstein, Carmela R. Abraham, Eliezer Masliah

Journal:

The American Journal of Pathology

Year:

2000

Language:

english

File:

PDF, 402 KB

english, 2000

40

Identification of a novel serine protease-like molecule in human brain

Barbara Meckelein, Derek C.L Marshall, Kelly-Jo Conn, Michael Pietropaolo, William Van Nostrand, Carmela R Abraham

Journal:

Molecular Brain Research

Year:

1998

Language:

english

File:

PDF, 1.69 MB

english, 1998

41

Reactive astrocytes and α1-antichymotrypsin in Alzheimer’s disease

Carmela R Abraham

Journal:

Neurobiology of Aging

Year:

2001

Language:

english

File:

PDF, 75 KB

english, 2001

42

P1-201 In search for APP-binding proteins

Carmela R. Abraham, Sunyoung Oh, Aviva Ellenstein, Eric Berg, Peter O'Connor, Catherine Costello, William E. Van Nostrand, Rachael Neve

Journal:

Neurobiology of Aging

Year:

2004

Language:

english

File:

PDF, 172 KB

english, 2004

43

Increased microglial activation and protein nitration in white matter of the aging monkey☆

Jacob A. Sloane, William Hollander, Mark B. Moss, Douglas L. Rosene, Carmela R. Abraham

Journal:

Neurobiology of Aging

Year:

1999

Language:

english

File:

PDF, 642 KB

english, 1999

44

Evidence for local production of acute phase response apolipoprotein serum amyloid A in Alzheimer's disease brain

Jun-shan Liang, Jacob A Sloane, John M Wells, Carmela R Abraham, Richard E Fine, Jean D Sipe

Journal:

Neuroscience Letters

Year:

1997

Language:

english

File:

PDF, 106 KB

english, 1997

45

The Cytosolic Endopeptidase, Thimet Oligopeptidase, Destroys Antigenic Peptides and Limits the Extent of MHC Class I Antigen Presentation

Ian A. York, Annie X.Y. Mo, Kristen Lemerise, Wanyong Zeng, Yuelei Shen, Carmela R. Abraham, Tomo Saric, Alfred L. Goldberg, Kenneth L. Rock

Journal:

Year:

2003

Language:

english

File:

PDF, 664 KB

english, 2003

46

Human Endopeptidase (THOP1) Is Localized on Chromosome 19 within the Linkage Region for the Late-Onset Alzheimer Disease AD2 Locus

Barbara Meckelein, H.A.Rohan de Silva, Allen D. Roses, P.Nagesh Rao, Mark J. Pettenati, Pu-Ting Xu, Rosa Hodge, Marc J. Glucksman, Carmela R. Abraham

Journal:

Year:

1996

Language:

english

File:

PDF, 96 KB

english, 1996

47

Promoter methylation and age-related downregulation of Klotho in rhesus monkey

Gwendalyn D. King, Douglas L. Rosene, Carmela R. Abraham

Journal:

Year:

2012

Language:

english

File:

PDF, 1.09 MB

english, 2012

48

Huntington's disease: Changes in striatal proteins reflect astrocytic gliosis

Dennis J. Selkoe, Fernando J. Salasar, Carmela Abraham, Kenneth S. Kosik

Journal:

Year:

1982

Language:

english

File:

PDF, 2.99 MB

english, 1982

49

Alzheimer's disease: Immunoreactivity of neurofibrillary tangles with anti-neurofilament and anti-paired helical filament antibodies

Chaudri G. Rasool, Carmela Abraham, Brian H. Anderton, Margaret Haugh, Jacob Kahn, Dennis J. Selkoe

Journal:

Year:

1984

Language:

english

File:

PDF, 4.52 MB

english, 1984

50

Synthesis and secretion of active α1-Antichymotrypsin by murine primary astrocytes

Kazutomi Kanemaru, Barbara Meckelein, Derek C.L. Marshall, Jean D. Sipe, Carmela R. Abraham

Journal:

Neurobiology of Aging

Year:

1996

Language:

english

File:

PDF, 839 KB

english, 1996